About us - Publications

Articles

  • Teufel A, Maass T, Strand S, Kanzler S, Galante T, Becker K, Biesterfeld S, Westphal H, Galle PR. Liver specific Ldb1 deletion results in enhanced liver cancer development. J Hepatol, under revision, 2009.
  • Buchkremer S, Hendel J, Krupp M, Weinmann A, Schlamp K, Maass T, Staib F, Galle PR, Teufel A. Library of Genetic Associations: Curating the complex basis of Liver Diseases. BMC Genomics, under revision 2009.
  • Maass T, Sfakianakis I, Staib F, Krupp M, Galle PR, Teufel A. Microarray-based gene expression analysis of Hepatocellular carcinoma. Curr. Genomics, under revision. 2009.
  • Hov JR, Keitel V, Laerdahl JK, Spomer L, Buchert E, ElSharawy A, Melum E, Boberg KM, Manke T, Balschun T, Schramm C, Bergquist A, Weismüller T, Gotthardt D, Rust C, Henckaerts L, Onnie CM, Weersma RK, Sterneck M, Teufel A, Runz H, Stiehl A, Ponsioen CY, Wijmenga C, Vatn MH, for the IBSEN study group, Stokkers P, Vermeire S, Mathew CG, Lie BA, Beuers U, Manns MP, Schreiber S, Schrumpf E, Häussinger D, Franke A, Karlsen TH. Bile acid receptor TGR5 associates with primary sclerosing cholangitis and ulcerative colitis. Gastroenterology, under review, 2009.
  • Schuster A, Schilling T, De Laurenzi V, Koch AF, Seitz S, Teufel A, Staib F, Melino G, Stremmel W, Krammer PH and Müller M. ΔNp73 confers chemoresistance in hepatocellular carcinoma by blocking apoptosis signaling via death receptors and mitochondria. Gastroenterology, under review, 2009.
  • Maass, Thieringer FR, Mann A, Longerich T, Schirmacher P, Galle PR, Teufel A, Kanzler S. Liver specific overexpression of Platelet derived growth factor (PDGF)-B accelerates liver cancer development in chemically induced liver carcinogenesis. Int J Cancer, under revision, 2009.
  • Teufel A, Weinmann A, Kahaly GJ, Centner C, Piendl A, Wörns M, Lohse AW, Galle PR, Kanzler S. Concurrent Autoimmune Diseases in Patients with Autoimmune Hepatitis, J Clin Gastro, in press 2009.
  • Weber A, Boger R, Vick B, Urbanik T, Haybaeck J, Zoller S, Teufel A, Krammer PH, Opferman JT, Galle PR, Schuchmann M, Heikenwalder M, Schulze-Bergkamen H. Hepatocyte-specific deletion of the anti-apoptotic protein Mcl-1 triggers proliferation and hepatocarcinogenesis in mice. Hepatology, accepted for publication, 2009.
  • Karlsen TH, Franke A, Melum E, Kaser A, Hov JR, Balschun T, Lie BA, Bergquist A, Schramm C, Weismüller TJ, Gotthardt D, Rust C, Philipp EE, Fritz T, Henckaerts L, Weersma R, Stokkers P, Ponsioen CY, Wijmenga C, Sterneck M, Nothnagel M, Hampe J, Teufel A, Runz H, Rosenstiel P, Stiehl A, Vermeire S, Beuers U, Manns M, Schrumpf E, Boberg KM, Schreiber S. Genome-wide association analysis in primary sclerosing cholangitis. Gastroenterology. Nov 25. [Epub ahead of print]. 2009.
  • Seitz SJ, Schleithoff ES, Koch A, Schuster A, Teufel A, Staib F, Stremmel W, Melino G, Krammer PH, Schilling T, Müller M. Chemotherapy-induced apoptosis in hepatocellular carcinoma involves the p53 family and is mediated via the extrinsic and the intrinsic pathway. Int J Cancer. Aug 26. [Epub ahead of print]. 2009.
  • Wang C*, Maass T*, Krupp M, Thieringer F, Strand S, Wörns MA, Galle PR, Teufel A. A systems biology perspective on CCC development. Focus on MAPK-Signaling and extracellular environment. J Hepatol. 50: 1122-31, 2009.
  • Teufel A, Galle PR, Kanzler S. Update on autoimmune hepatitis. World J Gastroenterol. 2009 15: 1035-41, 2009
  • Wörns MA, Weinmann A, Pfingst K, Schulte-Sasse C, Messow CM, Schulze-Bergkamen H, Teufel A, Schuchmann M, Kanzler S, Düber C, Otto G, Galle PR. Safety and Efficacy of Sorafenib in Patients With Advanced Hepatocellular Carcinoma in Consideration of Concomitant Stage of Liver Cirrhosis. J Clin Gastroenterol, 2009 Feb 25. [Epub ahead of print]
  • Teufel A, Weinmann A, Centner C, Piendl A, Lohse AW, Galle PR, Kanzler S. Hepatocellular carcinoma in patients with autoimmune hepatitis. World J Gastroenterol. 15: 578-82, 2009.
  • Moehler M, Sprinzl MF, Abdelfattah M, Schimanski CC, Adami B, Godderz W, Majer K, Flieger D, Teufel A, Siebler J, Hoehler T, Galle PR, Kanzler S. Capecitabine and irinotecan with and without bevacizumab for advanced colorectal cancer patients. World J Gastroenterol. 15:449-56, 2009.
  • Teufel A, Maass T, Galle PR, Malik N. The longevity assurance homologue of yeast lag1 (Lass) gene family (review). Int J Mol Med. 23: 135-40, 2009.
  • Herzer K, Hofmann TG, Teufel A, Schimanski CC, Moehler M, Kanzler S, Schulze-Bergkamen H, Galle PR. IFN-alpha-induced apoptosis in hepatocellular carcinoma involves promyelocytic leukemia protein and TRAIL independently of p53. Cancer Res. 69: 855-62, 2009.
  • Vick B, Weber A, Urbanik T, Maass T, Teufel A, Krammer PH, Opferman JT, Schuchmann M, Galle PR, Schulze-Bergkamen H. Knockout of myeloid cell leukemia-1 induces liver damage and increases apoptosis susceptibility of murine hepatocytes. Hepatology. 49: 627-36, 2009.
  • Gorivodsky M, Mukhopadhyay M, Wilsch-Braeuninger M, Phillips M, Teufel A, Kim C, Malik N, Huttner W, Westphal H. Intraflagellar transport protein 172 is essential for primary cilia formation and plays a vital role in patterning the mammalian brain. Dev Biol. 325: 24-32, 2009.
  • Schlamp K, Weinmann A, Krupp M, Maass T, Galle PR, Teufel A. BlotBase: A northern blot database. Accepted for publication, Gene, 2008.
  • Foltys D, Moench C, Burck I, Hoppe-Lotichius M, Schad A, Teufel A, Heise M, Otto G. [The Solid Pseudopapillary Tumor (SPT) - a Rare Neoplasm of the Pancreas.] Z Gastroenterol. 46:689-94, 2008.
  • Thieringer FR, Maass T, Czochra P, Klopcic B, Conrad I, Friebe D, Schirmacher P, Lohse AW, Galle PR, Teufel A, Kanzler S. Spontaneous hepatic fibrosis in transgenic mice overexpressing PDGF-A. Gene. 2008 Jun 10. [Epub ahead of print]
  • Teufel A, Weinmann A, Centner C, Piendl A, Lohse AW, Galle PR, Kanzler S. Hepatocellular Carcinoma in Patients with Autoimmune Hepatitis. Accepted for publication, World J Gastroenterol, 2008.
  • Worns MA, Teufel A, Kanzler S, Shrestha A, Victor A, Otto G, Galle PR, Hohler T, Incidence of HAV and HBV infections and vaccination rates in patients with autoimmune liver diseases. Am J Gastroenterol. 103: 138-46, 2008.
  • Kanzler S, Teufel A, Galle PR. [Liver Function Test to Predict Hepatic Failure after Liver Resection – Expensive and without Clinical Relevance?] Zentralbl Chir. 132: 267-73, 2007.
  • Drescher D, Moehler M, Gockel I, Frerichs K, Muller A, Dunschede F, Borschitz T, Biesterfeld S, Holtmann M, Wehler T, Teufel A, Herzer K, Fischer T, Berger MR, Junginger T, Galle PR, Schimanski CC. Coexpression of receptor-tyrosine-kinases in gastric adenocarcinoma - a rationale for a molecular targeting strategy? World J Gastroenterol. 13: 3605-9, 2007.
  • Teufel A, Staib F, Kanzler S, Weinmann A, Schulze-Bergkamen H, Galle PR. Genetics of hepatocellular carcinoma. World J Gastroenterol. 13: 2271-82, 2007.
  • Teufel A, Weinmann A, Krupp M, Budinger M, Galle PR. Genome-wide analysis of factors regulating gene expression in liver. Gene 389: 114-21, 2007.
  • Teufel A, Worns M, Weinmann A, Centner C, Piendl A, Lohse AW, Galle PR, Kanzler S. Genetic association of autoimmune hepatitis and human leucocyte antigen in German patients. World J Gastroenterol. 12: 5513-6, 2006.
  • Schimanski CC, Bahre R, Gockel I, Muller A, Frerichs K, Horner V, Teufel A, Simiantonaki N, Biesterfeld S, Wehler T, Schuler M, Achenbach T, Junginger T, Galle PR, Moehler M. Dissemination of hepatocellular carcinoma is mediated via chemokine receptor CXCR4. Br J Cancer. 95: 210-7, 2006
  • Teufel A, Krupp M, Weinmann A, Galle PR. Current bioinformatics tools in genomic biomedical research. Int J Mol Med. 17: 967-73, 2006.
  • Wang C*, Teufel A*, Galle PR, Lohse AW, Herkel J. Characterization of the human SLA/LP gene and its conserved orthologs in mouse, fish, fly, and worm. World J Gastroenterol. 12: 902-7, 2006.
  • Krupp M, Weinmann A, Galle PR, Teufel A. Actin binding LIM protein 3 (abLIM3). Int J Mol Med. 17: 129-33, 2006.
  • Schuchmann M, Schulze-Bergkamen H, Fleischer B, Schattenberg J, Siebler J, Weinmann A, Teufel A, Wörns M, Fischer T, Strand S, Lohse AW, Galle PR. Histone deacetylase inhibition by valproic acid down regulates c-FLIP and sensitizes hepatoma cells towards CD95- and TRAIL- receptor mediated apoptosis and chemotherapy. Int J Oncol 15: 227-30, 2006.
  • Weinmann A, Galle PR, Teufel A. LASS6, a novel member of the Longevity Assurance protein family. Int J Mol Med. 16: 905-10, 2005.
  • Weinmann A, Galle PR, Teufel A. In silico characterization of an iroquois family related homeobox protein (IFRX). Int J Mol Med. 16: 443-8, 2005.
  • Teufel A, Weinmann A, Galle PR, Lohse AW. In silico characterization of LZTS3, a potential tumor suppressor. Oncol Reports. 14: 547-51, 2005.
  • Moehler M, Teufel A, Galle PR. New chemotherapeutic strategies in colorectal cancer. Recent Results Cancer Res. 165: 250-9, 2005.
  • Teufel A, Weinmann A, Galle PR, Lohse AW. Characterization of OEBT, a LIM Protein. Int J Mol Med. 15 (3): 513-18, 2005.
  • Teufel A, Steinmann S, Siebler J, Zanke C, Hohl H, Adami B, Schroeder M, Klein O, Hohler T, Galle PR, Heike M, Moehler M. Irinotecan plus folinic acid/continuous 5-fluorouracil as simplified bimonthly FOLFIRI regimen for first-line therapy of metastatic colorectal cancer. BMC Cancer. 4(1): 38, 2004.
  • Teufel A, Wong EA, Mukhopadhyay M, Malik N, Westphal H. FoxP4, a novel forkhead transcription factor. Biochim Biophys Acta. 1627 (2-3):147-52, 2003.
  • Mukhopadhyay M*, Teufel A*, Yamashita T*, Agulnick AD, Chen L, Downs KM, Schindler A, Grinberg A, Huang SP, Dorward D, Westphal H. Functional ablation of the mouse Ldb1 gene results in severe patterning defects during gastrulation. Development 130: 495-505, 2003.
  • Teufel A, Malik N, Mukhopadhyay M, Westphal H. Frcp1 and Frcp2, two fibronectin type III repeat containing genes. Gene 297: 79-83, 2002.
  • Miamoto T, Kawahara A, Teufel A, Mukhopadhyay M, Zhao Y, David IB, Westphal H. Molecular cloning and expression analysis of the mouse mbx, a novel homeobox gene in mouse development. Dev Genes Evol 212: 104-6, 2002.
  • Schulze-Bergkamen H, Zuna I, Teufel A, Stremmel W, Rudi J. Treatment of Advanced Gastric Cancer with Etoposid, Folinic Acid and Fluorouracil in the Clinical Setting - Efficiancy of Therapy and Value of Serum Tumor Markers. Med Oncol. 19: 43-53, 2002.
  • Teufel A, Lehnert T, Stremmel W, Rudi J. Chemotherapy with gemcitabine in patients with advanced gallbladder carcinoma. Z Gastroenterol 38: 909-12, 2000.
  • Teufel A, Lehnert T, Stremmel W, Rudi J. Long-Term Clinical Remission in a Patient with Metastatic Gastric Cancer after Palliative Chemotherapy. Onkologie 23: 464-6, 2000.
  • Heils A, Teufel A, Petri S, Stober G, Riederer P, Bengel D, Lesch KP. Allelic variation of human serotonin transporter gene expression. J Neurochem 66: 2621-4, 1996.
  • Heils A, Teufel A, Petri S, Seemann M, Bengel D, Balling U, Riederer P, Lesch KP. Functional promoter and polyadenylation site mapping of the human serotonin (5-HT) transporter gene. J Neural Transm Gen Sect 102: 247-54, 1995.

Book chapters

  • Teufel A. BASICS Humangenetik. Elsevier Verlag. In press. 2010
  • Teufel A, Galle PR. Genetics of Hepatocellular Carcinoma. In: Dionigi I. Recent Advances in Liver Surgery. Landes Bioscience. 2008.
  • Teufel A, Krupp M, Weinmann A, Galle PR. Current bioinformatics tools in genomic biomedical research. Bioinformatics – The Road Ahead. Icfai University Press. 2008.
  • Lesch KP, Balling U, Seemann M, Teufel A, Bengel D, Heils A, Godeck P, Riederer P. Molecular heterogeneity of neurotransporters: implications for neurodegeneration. In: Mizuno Y et al.: Advances in Research on Neurodegenerative Vol. 3 & 4. J Neural Transm (Suppl. 49) 155-167. 1997.